Multiple Tables into 1 Table??

I started learning MySQL about 2 weeks ago and have made HUGE strides in automating tasks at work that should have been outdated as a corporate process eons ago.

What I want to do now is take price files from my suppliers that are not the same format and put them into 1 table allowing me to consolidate multiple vendors into 1 file as I only care about certain fields and of these fields they will contain the same information for every supplier.

1 supplier may have the following
Part Number
Buy minimums
Buy Multiples
Package size
cost

Another Supplier may have
Part Number
Base Qty
cost
resale 1
resale 2
resale 3

My thoughts on making this happen are
1) define the fields that will be common and create my table in sql accordingly
2) run a query on each suppliers price file that will place data in the created table

If that is so, what would I be doing to the table in my query, updating or appending the results? I ask as the information and quantity of part numbers may vary due to new products or deletions when updated price files are supplied

thanks